Permeability of the mitochondrial membrane to bicarbonate ions

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Permeability of the mitochondrial membrane to bicarbonate ions.

Osmotic-swelling techniques show that HCO3- enters mitochondria by an electrogenic process, effectively HCO3- uniport, under non-energized conditions. This mode of translocation accounts for previous reports of non-entry of HCO3- in experiments with energy-linked Ca2+ uptake. The effects of HCO3- on mitochondrial respiration are reported and discussed.

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The Structure of the Mitochondrial Membrane: Inferences from Permeability Properties

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ژورنال

عنوان ژورنال: Biochemical Journal

سال: 1977

ISSN: 0264-6021

DOI: 10.1042/bj1660137